The 13th Symposium will comprise
- Plenary lectures by invited speakers
- Short oral presentations
- Poster sessions.
The posters will be displayed on June 22th and will stay during all Symposium.
Preliminary Topics
- Gametes antigenicity and gametes interactions
- Innate and adoptive immune mechanisms in reproduction
- Tregs and pregnancy maintenance
- Immune-endocrine interactions in reproduction
- Mechanisms of immune regulation in implantation and pregnancy
- Cytokines in implantation and pregnancy
- Mucosal immunity
- Immunological problems of infertility
- Pregnancy loss and implantation failures
- Stem cells in reproduction
Invited speaker:
B. Anne Croy, DVM, PhD.
Roles of leukocytes in the physiological changes of pregnancy |
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Dr. Croy is a veterinary graduate who pursed an academic career in anatomical sciences. In 2004, she was awarded the Canada Research Chair in Reproduction, Development and Sexual Function at Queen’s University. Dr. Croy’s research program focuses upon the regulation and functions of transient pregnancy-associated uterine natural killer cells in animal models. Her studies address roles of these cells in endometrial angiogenesis supporting healthy gestation and as potential players in the pathogenesis of pre-eclampsia and spontaneous fetal loss. |
| To support her morphological and gene expression studies in pregnant mice, Croy embraced the technologies of continous radiotelemetry and high frequency ultrasound to advance understanding of the roles of the immune system in blood pressure regulation and cardiovascular disease programming in normal pregnancies and in pregnancies with complications such as incomplete spiral arterial modification and type1 diabetes. She will discuss her current findings. |
Brian Acacio MD, FACOG
Onco-Fertility |
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Brian Acacio, MD, FACOG, is a recognized leader in reproductive medicine – reproductive immunology, the treatment of recurrent pregnancy loss (miscarriages) and implantation failure (prior IVF failures). He is a Medical Director/owner of Acacio Fertility Center in Laguna Niguel, CA, USA. The Center is one with the highest successful pregnancy rate in USA and worldwide. Before opening his Center in early 2008, he was Reproductive Endocrinology and Infertility Division Director of Department of Obstetrics and Gynecology at University of |
| California Los Angeles (UCLA), and Medical Director of SIRM-Orange County, CA. Dr. Acacio give lectures and publish extensively in the field of reproductive medicine in peer-reviewed journals and book chapters. The results from his scientific work have specific practical use and have been cited worldwide by practitioners and scientists in the field. |
Carolyn B. Coulam, MD, Professor
Does immunotherapy for treatment of reproductive failure enhance live births |
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Carolyn Coulam, M.D. is board certified in the specialty of obstetrics and gynecology and in the sub-specialty of reproductive endocrinology and has served as chair of the Division of Reproductive Endocrinology at the Mayo Clinic where she established the first in vitro fertilization (IVF) program at this institution, in 1983. She became professor at the Mayo Medical School in 1984. Since then she has served as chair of the Division of Reproductive Biology at the University of Pittsburgh, as the Medical Director of the Center for Reproduction and Transplantation |
| in Indianapolis, Indiana, as Director of Reproductive Immunology at the Genetics & IVF Institute in Fairfax, Virginia, as National Director of Reproductive Immunology at the Center for Human Reproduction (CHR) in Illinois and as Medical Director SIRM-Chicago. Dr. Coulam has served as managing editor of the American Journal or Reproductive Immunology. She has more than 200 publications in peer-reviewed journals to her credit and has edited a major reference textbook entitled “Immunologic Obstetrics” published by W.W. Norton. Today, Dr. Coulam is Director of Recurrent Pregnancy Loss and Director of Research at the Reproductive Medicine Institute in Chicago |
David A. Clark, Professor MD, PhD, FRCP(C), FRCP(Edin.).
Is "the seed" or "the soil" the more important of the success or failure of reproduction?
From man to mouse and back again.
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Emeritus Professor of Medicine, Departments. of Medicine, Molecular Medicine & Pathology, Obstetrics & Gynecology, McMaster University, Ontario, Canada, Affiliate Scientist, Toronto General Research Institute (Transplant Immunology/Cell Biology Divisions). M.D. University of Western Ontario, Canada (1967); Diplomate American Board of Internal Medicine, Boston, Mass., USA (1972); Fellow, Royal College of Physicians and Surgeons of Canada (1974); Ph.D. (Regulation of Cytotoxic T lymphocytes), University of Toronto (1977); Fellow of the |
| Royal College of Physicians (Edinburgh, UK, for contributions to Immunology of Reproduction) (2001). President ASRI (1996-1998), President ISIR (1998-2001), President d’Honneur, ISIR (2001- ). Has served on Editorial Boards of the Journal of Immunology, Journal of Reproductive Imuunology, Americal Journal of Reproductive Immunology , Journal of Assisted Reproduction and Genetics, and as Associate Editor of AJRI and Section editor of JARG. Peer-reviewed publications 199, non-peer reviewed publications including book chapters 127. Two current peer review grants. |
Eytan R. Barnea, M.D., FACOG
Preimplantation Factor (PIF*): Necessary for pregnancy. Instrumental in autoimmune and transplant regimen treatment. |
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Eytan R. Barnea investigates early pregnancy, translating basic observations into clinical applications. He is the discoverer of the PreImplantation Factor (PIF) an embryo-derived compound essential for pregnancy and instrumental for non-pregnant autoimmune scenarios. Founder of S.I.E.P., the Society for the Investigation of Early Pregnancy, he co-edited The First Twelve Weeks of Gestation (Springer-Verlag), Implantation and Early Pregnancy in Humans (Parthenon), Embryonal Medicine and Therapy (OUP), and Cancer & Pregnancy (Springer- |
| Verlag) and was editor-in-chief and founder of E.P.B.M. Early Pregnancy: Biology and Medicine peer-reviewed specialty journal. Director of Obsterics Gynecology and Reproduction at CAMcare, Dr. Barnea is a full-time clinician, an Associate Clinical Professor of Ob&Gyn and Reproduction at UMDNJ/RWJMS, and is double board certified in Ob/Gyn and Reproductive Endocrinology. He received Elkeles Prize recipient as Scientist of the Year in Medicine (1989), upon the Israeli Health Ministry /Jewish National Fund's recommendation. |
Gerard Chaouat, MD. PhD, Professor
Presented seminal plasma peptides but not the MHC of an immunizing cell determine the outcome of lymphocyte immunization in the CBA x DBA/2 model. |
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Dr Gérard CHAOUAT initially worked on enhancing antibodies and suppressor T cells. Placental suppression was then studied, and a low MW molecule isolated inducing anergy on TcR activated T lymphocytes. Other suppressive pathways were studied with D. Clark (TGF beta 2) and J. Szekeres Bartho . Dr Chaouat centres on the utero placental cytokine network, initially in the CBA x DBA/2 murine abortion model, which demonstrated the involvement of “immunotrophic” cytokines as |
| well as late the role of Th2 cytokines and placental tau interferons with J Martal. Current topics are the role of cytokines in implantation, with emphasis on LIF and IL-11 in human, IL 11, IL 12, IL 13 , IL 14 and IL 18 in mice. Another main programme was materno foetal transmission of HIV. Dr G Chaouat was member of the scientific council of CNRS, is President d’honneue of ISIR and directeur de recherché emeritus at CNRS |
Gil Mor, MD, PhD, Professor
Inflammation and pregnancy: the good and the bad |
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Gil Mor, M.D., Ph.D. is a Professor of Obstetrics and Gynecology and Reproductive Science at Yale University School of Medicine. In his research he examines topics related to the immunology of implantation, the role of apoptosis in tissue remodeling and cancer, as well as the role of inflammation in cancer formation and progression. At the present time he is the Director of the Reproductive Immunology Unit and the Translational Research Program “Discovery To Cure” at Yale University. Dr. Mor is the Editor in Chief of the American Journal of Reproductive |
| Immunology. Dr. Mor is funded by grants from National Institute on Child Health and Human Development and National Cancer Institute as well as several pharmaceutical companies and is widely published in the area of immunology and reproduction with more than 220 publications and is the editor of a two books on “Immunology of pregnancy” and “Apoptosis and Cancer”. Dr. Mor is recipient of several national and international prizes, including the J. Christian Herr Award-from the Society for Reproductive Immunology Dr. Mor is member of the American Association for Cancer Research, the Society for Gynecologic Investigation and the American Society of Reproductive Immunology. He is also Honorary member of several scientific societies in South America and Europe. |
Hans Donat, Prof. Dr. med. habil.
Immunology of Breast Neoplasms |
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After my study at the High Medical Institute in Sofia and the Medical Academy of Magdeburg 1965 I received the doctorate of medicine. In 1970 I was given the Medical Specialists Certificate of Gynecology and Obstetrics and then worked as Senior Physician in the Gynecological Hospital of the Medical Academy Magdeburg. Along with the special medical training I continued my scientific education and specialized in the diagnosis and therapy of infertility. I familiarized with this branch and started scientific research of immunological and andrological problems. In 1981 I did the advanced doctorate in -Immunologic causes to |
| demonstrate tissue-bound and humoral antibodies in sterile couples-to gain the academic degree of Doctor of Medical Science and 1984 I became Associated Professor in gynecology and obstetrics. I left the University in 1993 and started with my own gynecological practice and founded the Institute for Reproductive Immunology. I am a member of the International Coordination Committee for Immunology of Reproduction and I attended regularly the International Symposia in Varna. |
Hiroaki Shibahara, M.D., Ph.D. Professor
Update of our clinical and basic research on immunologically infertile male. |
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Prof Hiroaki Shibahara is a chief of Department of Obstetrics and Gynecology, School of Medicine, Jichi Medical University, and Center for Reproductive Medicine, Jichi Medical University Hospital, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan. He have next awards: 1995 - Hyogo Prefectural Society of Obstetrics and Gynecology;1998- Japan Society of Fertilization and Implantation and 2003 - Japan Society of Fertility and Sterility. He is a councilor of American Society of Reproductive Immunology, Chair of the 3 annual domestic meetings – |
| 2007-2013 and Exective Board Members of 3 Japan Society. Prof Shibahara is Board Member of Japan Society of Gynecologic and Obstetric Endoscopy, Japan Society for Reproductive Immunology, Japan Society of Andrology and Ethics Committee Member of Japan Society for Reproductive Medicine. He is a member of Editorial board of Reproductive Medicine and Biology (Editor-in-associate chief, Reviewing editor), Current Women’s Health Reviews and Open Women Health Journal |
Ian Surgent, Professor
Placental microvesicles and exosomes: their role in normal pregnancy and pre-eclampsia |
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Ian Sargent is an immunologist based in the Nuffield Department of Obstetrics and Gynecology, University of Oxford, UK, where he is Professor of Reproductive Science. He has worked in the field of Reproductive Immunology for the past 30 years and has over 150 publications on a wide range of topics including pre-eclampsia, feto-maternal cell traffic, trophoblast microparticles, HLA-G and early human embryo development and implantation. He was Scientific Director of the Oxford IVF Unit for over 20 years. He is a member of the Executive Councils of |
| the International Society for Immunology of Reproduction and European Society for Reproductive Immunology. |
Jana Peknicova, Assoc. prof. RNdr., PhD.
Effect of endocrine disruptors on reproductive parameters and expression of selected testicular genes in male mice in vivo. |
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Director of the Institute of Biotechnology AS CR, v.v.i. and Head of Laboratory of Diagnostics for Reproductive Medicine, Videnska 1083, 142 20 Prague 4, Czech Republic. The main activities of her research are related to the role of selected sperm proteins in fertilization as well as the role of reproductive fluids in the early stages of fertilization. She investigate and effects of selected pollutants on viability and physiology of cells in vitro and on reproduction of mice in vivo. Her publication activities include more than 90 original scientific papers. She is a |
| lecturer on “Molecular mechanisms of fertilization” for elaboration of diploma and PhD thesis at the Faculty of Sciences, Charles University, Prague. |
Julia Szekeres-Bartho, MD, Professor
Mechanisms controlling trophoblast invasion. |
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Julia Szekeres-Bartho is a full professor and chair of the Department of Medical Microbiology and Immunology, Medical School of Pécs University, Hungary. Her research has focused on, the interaction of reproductive hormones and the immune system. Her group have discovered and characterized a progesterone induced protein called PIBF. By signaling via a novel form of the IL-4 receptor this molecule induces a TH2 dominant cytokine production, and exerts an anti-abortive effect in mice. PIBF production is also a characteristic feature of normal |
| human pregnancy, and determination of PIBF concentration in urine might be of use for the diagnosis of threatened premature pregnancy termination. They have identified a number of PIBF-regulated genes that play a role during the establishment and maintenance of pregnancy. She has published close to 200 papers in international journals. |
Katja Teerds, Assoc. Professor, PhD
Postnatal Testicular Development: Role of Thyroid Hormones |
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Katja Teerds is trained as a biologist and did a PhD at the Medical Faculty of Utrecht University. After her PhD she joined the Department of Functional Morphology, division of Cell Biology where she continued her research on Leydig cell development in the testis. She received an honorable grant for excellent research from the Netherlands Academy of Arts and Sciences in 1991 to continue her research on Leydig cells. She was appointed assistant professor in Cell Biology in 1995. The focus of her research had by that time expanded to follicle development in the ovary as well. In 2002 she was appointed as associate |
| professor at the Department of Animal Sciences, division of Human and Animal Physiology, where she continued her research on testicular and ovarian development and function. Beside research she developed, coordinates and teaches courses in Behavioural Endocrinology and Integrated Neuroendocrinology to BSc and MSc students. Since she moved to Wageningen she has supervised over 50 MSc thesis projects and 5 PhD projects. She is at present treasurer of the Royal Netherlands Zoological Society, member of the executive council of the European Workshop for Molecular and Cellular Endocrinology of the Testis, member of the Publication Committee of the American Society of Andrology, and is member of the editorial boards of Journal of Andrology, Biology of Reproduction and Reproductive Biology and Endocrinology. She is (co)author of over 90 peer-reviewed papers and book chapters. |
Liselotte Mettler, Professor
Endometriosis and adenomyosis: Do they have immunological connections? |
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Professor Dr. med. Liselotte Mettler was born on 6.6.39 in Vienna, Austria. From 1959-1981 medical studies, doctorate, medical specialist training, habilitation and professorship in Tübingen, Vienna and Kiel. 1981-2007 she was Deputy Director of the Department of Obstetrics and Gynaecology, University Hospitals Schleswig-Holstein; 2002-2007-Head of the Gynaecological Endocrinology and Reproductive Medicine Division at the same department. Her main fields of activity are reproductive medicine, gynaecological endoscopy and gynaecological |
| endocrinology. Prof. Mettler is actively participating in many societies and organizations. She has written over 700 publications, 20 books and 4 textbooks. Since 1973 she attended nearly all major endoscopic conferences in the world, particularly all AAGL meetings. All her profession life was spent around endoscopic gynaecologic surgery and Reproductive Medicine. Since 2008 she is Emeritus professor at the Department of O/G, University Hospitals Schleswig-Holstein, Honorary Patron of the Kiel School of Gyne Endoscopy and Reproductive Medicine, Lecturer at the Harvard Medical School, Dubai Healthcare City, Dubai, U.A.E and general manager of Gyne Consulting Kiel. Currently she serves as General Secretary for the International Academy of Human Reproduction. Prof.L. Mettler is a Honorary member of ICCCR. |
Maciej Kurpisz, PhD, Professor
Semen inflammation, innate immunity and sperm quality |
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Professor Kurpisz is a Head of Department of Reproductive Biology and Stem Cells, Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland. He has graduated Poznan Medical University. Then he was promoted as MD in Immunology (1982) and Ph.D. in Genetics (1989), since 1996, he is appointed as a full professor. He performed professional training in UK, USA, Japan and Germany. His main research topics include reproductive immunology and genetics |
| as well as stem cells and regenerative medicine while clinical practice includes infertility, andrology and anti-aging. He has published over 320 papers, half referred in PubMed, successfully sought 56 grants, supervised 10 doctorates and 23 masters. He is a member of board of 9 international journals and recipient of 20 professional awards including Dr. h. c. from Lviv Medical University. He is a current President of European Society for Reproductive Immunology. |
Marie-Pierre Piccinni, Dr., PhD
Th1, Th2 and Th17 CD4+ T helper subpopulations and human pregnancy development |
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Marie-Pierre Piccinni received her first PhD in Hematology from the Scientific, Medical and Technologic University Joseph Fourier of Grenoble (France) and her second PhD in Clinical Immunology from the University of Bari (Italy) in 1999. She is assistant Professor at the Faculty of Medicine, University of Florence (I) and she is the chief of the Allergology Laboratory in the “Immunoallergology Unit” of the Centro Ospedaliero Universitario di Careggi ( Careggi Hospital of Florence). Since coming to the Department of Internal Medicine of the University of |
| Florence, she took the lead of the research focused on to feto-maternal immune interactions and on the devising of new diagnostic and therapeutic immune strategies for female infertility. Her scientific output consists of 123 publications, 68 of which published in international per-review journals. Her global impact factor is > 370 and mean impact factor per paper is 5.44 . |
Milena Mourdjeva, PhD
Immunoregulatory factors of early pregnancy |
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Milena Mourdjeva is working in the field of reproductive immunology and stem cells. She is head of Department Molecular Immunology at IBIR-BAS. Supervisor of PhD and Master Theses programmes. She is co-author of over 15 scientific papers with more than 45 citations. Mourdjeva is participant in ReProForce project under REGPOT-2009-1; Principal Investigator or Group leader in national projects funded by National Science Fund of the Bulgarian Ministry of Education and Science. Recent work of Milena Mourdjeva is focused on comparative |
| investigation of mesenchymal stem cells (MSC) isolated from human bone marrow and adipose tissue. Her professional attempts are to reveal the importance of HLA-G and PIBF factors, produced by MSC and released in response to progesterone. Two main directions are followed – the immunoregulation properties of MSC and suppression of tumor cells proliferation by MSC. Dr Mourdjeva has an extended knowledge on molecular events occurring during apoptosis. |
Nelson Fernández, Professor of Immunology
Mapping histocompatibility molecules on trophoblast cells. on bioinformatics, bioimaging and proteomics: Relevance for fetomaternal interaction |
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Professor Fernández did a BSc at Kings College in London and a trained as an immunologist at the Royal London Hospital. He was appointed as a lecturer in immunology at the University of Essex in 1990 and was promoted to Professor in 2000. Professor Fernández has served as Head of Molecular Medicine and Director of the Bioimaging Core Facility at Essex, until October 2011. Currently his main activities involve teaching and research. His teaching involves undergraduate and graduate (research) modules; at undergraduate level he has developed core modules in immunology for BSc students in the science faculty. He |
| also teaches immunology for post-graduate courses at masters’ level in Biotechnology and in Molecular Medicine. Over the years he has supervised over 15 PhD theses to completion. Currently he has 7 PhD students. His current research focuses on innate recognition and reproductive immunology. In 1996 together with G. Voissin (Paris) and Maciej Kurpisz, he participated in the foundation of the European Society of Reproduction Immunology (ESRI) of which he is currently member of the executive council. |
Shinji Komori, Professor
In vitro culture of immature oocyte |
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Professor Shinji Komori , Hyogo College of Medicine, Department of Obstetrics and Gynecology, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan,
Phone:81-798-45-6481,Fax-81-798-46-4163, E-mail: komor615@hyo-med.ac.jp. He is graduated form School of Medicine, Tokushima University (1982), Tokushima.
Experience: 1982 6 - Resident of Dept. of OB/GYN, Hyogo College of Medicine; 1984 6 - Senior resident of Dept. of OB/GYN, Hyogo College of Medicine; 1985 6 Research associate of Dept. of OB/GYN, Hyogo College of Medicine 1998 12 Assistant professor of Dept. of OB/GYN, Hyogo |
| College of Medicine; 2004 2 Associate professor of Dept. of OB/GYN, Hyogo College of Medicine; Associate professor of Laboratory of Developmental Biology and Reproduction, Institute for Advanced Medical Sciences, Hyogo College of Medicine; 2009 4 Professor and Chairman of Dept. of OB/GYN; Professor Dept. of Clinical Genetics, Hyogo College of Medicine; Specialties - Reproductive Immunology, Reproductive Endocrinology, Prenatal diagnosis |
Sotnikova Natalya, MD, PhD, Professor
The role of NK cells in early pregnancy |
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Medical Doctor, professor, head of the laboratory of Clinical Immunology of State Research Institute of Maternity and Childhood (Ivanovo, Russia), author more than 800 scientific publications, scientific supervisor of 78 PHD students |
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Peter Sedlmayr, M.D, Assoc.professor
IDO and the placenta: Still of interest? |
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Dr. Peter Sedlmayr is associate professor at the Institute of Cell Biology, Histology and Embryology, Center of Molecular Medicine at the Medical University of Graz, Austria. As a physician he is board certified for Immunology, Histology and Embryology, Internal Medicine and Clinical Chemistry. Starting from earlier research in tumor immunology he developed interest in reproductive immunology with special focus on the maternal immune cells at the endometrium and on mechanisms of feto-maternal tolerance. A further area of interest is single cell analysis in the |
| context of microchimerism and development of diagnostic applications in this field. |
Philippe Le Bouteiller, PhD
Decidual NK cells in early human pregnancy: unique killer properties |
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PhD - Paris 6 Univ (Biol. Reproduction). Post-doc 3-year training in Immunology/Molecular Biology: Clinical Research Centre, Immunological Medicine, Harrow, UK. One sabbatical year at Yale University, New Haven, CT, 9 years at the Centre d'immunologie Marseille-Luminy. I focused my interest on the functions of soluble and membrane-bound HLA-G isoforms in human embryo implantation, pregnancy outcome, and placental development. I established my own INSERM group in Toulouse on this topic and more recently on the effector functions of |
| decidual NK cells in normal and pathogen-infected pregnant uterus, and therapeutic applications of a monoclonal antibody directed against CD160 receptor. Current post: INSERM Director of Research, Principal Investigator of the "Immunity, pregnancy, therapeutics" group. Industrial collaboration: MATBiopharma, LFB Biotechnnologies. Member of the Editorial Boards of AJRI (1993-2008); JRI (2004-). Member of the EMBIC, reviewer of more than 12 specialized journals and Grant agencies: NIH-NIAID (USA), Wellcome Trust (UK), Science Foundation of Ireland, Biotechnology & Biological Sciences Research Council (UK), University of Koweit, The National Medical Research Council (Singapore), The Marsden Fund Council of New Zealand, French AERES. Invited speaker to ~60 Intl conferences since 2000, |
Qing-Yuan Sun, Professor
Heated spermatozoa: effects on embryonic development and epigenetics |
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Dr. Qing-Yuan Sun is a professor of reproductive biology in the Institute of Zoology, Chinese Academy of Sciences (CAS). He obtained his Ph.D. degree in embryology from Northeast Agricultural University in 1994. Then he got post-doc training in CAS, Bar-Ilan University and University of Missouri-Columbia. He became a full professor in 1998. His main research interest is cell and molecular biology of mammalian oocyte meiotic maturation and fertilization. He has authored or co-authored more than 220 papers in peer-review international journals, with more than 4000 citations. He is awardees of Distinguished Young Scientist of the |
| Chinese Academy of Sciences (1999), Outstanding Young Scientists of National Natural Science Foundation of China (2002), National Award for Distinguished Scholars Returned from Abroad (2003), Distinguished Youth of the Chinese Academy of Sciences (2003), National Award for Outstanding Youth (2004), National Natural Science Prize (2006), National Award for Outstanding Scientific and Technological Contribution (2011) etc. |
Raina N. Fichorova, MD, PhD
Reproductive hormones and inflamation |
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Dr. Fichorova’s research elucidates molecular mechanisms of innate immunity and susceptibility to infection in the female reproductive tract and the cytokine network in mothers and infants. Dr. Fichorova earned MD and PhD from the Medical University of Sofia, Bulgaria, and a Fellowship in Reproductive Immunology at the Department of Obstetrics, Gynecology and Reproductive Biology of Harvard Medical School (HMS) and Brigham and Women’s Hospital (BWH). For 5 years she worked as an Assistant Professor at her Alma Mater, where she |
| obtained awards from the National Research Fund of the Bulgarian Ministry of Science and Education and from the Medical Science Fund of Sofia Medical University. Since 1997, Dr. Fichorova has been full-time faculty at BWH and HMS. Dr. Fichorova chairs the Society for Internationally Trained Women Faculty and Fellows at BWH. Since funded in 2002, her laboratory at BWH has been continuously accredited by the College of American Pathologists. |
Rossitza Konakchieva, PhD, Assoc. Professor, D.Sc.
Physiological role of melatonin in human reproductive system – signaling, targets and receptor localization |
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Assoc. Professor Rossitza Konakchieva is a Head of Dept. Immunoneuroendocrinology, Head of Laboratory for Radioimmunology, Institute of Biology and Immunology of Reproduction and Director (Honorary) of Bachelor and Magister Programs in Cell Communication and Signalling, Department of Cell Biology and Histology, Faculty of Biology, Sofia University. Research profile of Dr. Konakchieva is Stress, neuroendocrine adaptation, pineal gland, immunomodulation. Professional experience: Management and supervision of research activities, principal investigator of national and international research |
| contracts, supervisor of 4 PhD and 8 Master theses. International experience: 1993-1994 - Centre for Reproductive Biology, MRC Unit, Edinburgh; 1996 – MPI of Psychiatry Munich; 1998-1999 - Laboratory of Neurobiology and Circadian Rhythms, CNRS, Strasbourg; 2000; 2002 – MPI of Psychiatry, MPI of Neurobiology, Munich. Dr. Konakchieva is member of ESRI, ESHRE, Bulgarian Society for Regenerative Medicine, editor of local scientific journal, and expert of scientific boards. Awards: Signum Laudis pro Scientiae Merritis for contribution in experimental reproductive medicine for research on cryopreservation of ovarian tissue. Author and co-author of 47 scientific papers with citation index of more than 140. E-mail: r_konakchieva@abv.bg |
Satish Kumar Gupta, PhD (1983)
Structural and functional attributes of zona pellucida glycoproteins |
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All India Institute of Medical Sciences, New Delhi; Deputy Director, National Institute of Immunology, New Delhi, Secretary-General, of ISIR (2010-2013). Dr. Gupta has made pioneering contributions in elucidating the biological functions of hormones such as hCG & GnRH and oocyte specific zona pellucida (ZP) glycoproteins by employing monoclonal antibodies. The B cell epitope mapping and cloning & expression studies have led to new insight in to the role of ZP glycoproteins during fertilization in humans. These studies have helped |
| in designing synthetic peptides/recombinant proteins as candidate immunogens to curtail fertility with specific reference to the management of street dog population. He is also investigating the role of cytokines in proliferation, invasion and differentiation of trophoblast cells. His group is also engaged in discovering natural compounds from medicinal plants with an anti-HIV activity. He has published extensively in international and national journals.. |
Soren Bohos Hayrabedyan, MD, PhD
Innate immune receptors and pathways in male reproduction. Their role and perturbation impact for male pathology. |
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Dr.Soren Hayrabedyan is currently working as Experienced Researcher at Project ReProForce under the ReGPot initiative of 7th EU FP. He currently works on the innate immune pathways perturbation in Sertoli cells and its impact on blood-testis barrier function and antigen presentation. He has graduated medicine, subsequently worked as Assistant Professor in Physiology, received PhD in Immunology in the Institute of Biology and Immunology of Reproduction. Dr. Hayrabedyan worked on problems of endometriotic angiogenesis and tumor markers |
| abundance, prostate cancer biology, introduced the digital pathology quantitative immunohistochemistry approach in endometriotic angiogenesis. He obtained Masters in Information systems and did a postdoc training in tumor starvation and proteomic protein binding studies at the Harvard Cutaneous Biology Research Center at Massachusetts General Hospital, Boston, USA. |
Takao Koike, M.D., Professor
Antyphospholipid Syndrom:2012 |
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Prof. Takao Koike is born October 4, 1947, Sapporo, Japan. Her present address: ?CEO of NTT Sapporo Medical Center, Sapporo, JAPAN. Education: 1972 M.D. Hokkaido University School of Medicine, Sapporo Japan. 1972-1975 Residency: Hokkaido University School of Medicine, Sapporo Japan. 1975-1978 Research Fellow, Department of Pathology, Hokkaido University School of Medicine, Sapporo, Japan. 1978-1980 Postdoctoral Research Fellow, Department of Medicine, University of California, San Francisco, USA. |
| 1980- 1981 Assistant Professor, Department of Pathology, Kyoto University Faculty of Medicine, Kyoto, Japan. 1982-1991 Assistant Professor, Department of Medicine, Chiba University School of Medicine, Chiba, Japan. 1992-2011 Professor Department of Medicine II, Hokkaido University Graduate School of Medicine. 2011-present Professor Emeritus Hokkaido University |
Udo R. Markert, PhD, Professor
MicroRNAs in trophoblastic cells |
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Prof. Udo Markert is Head of the Placenta Laboratories, the research unit of the Department of Obstetrics at the Friedrich-Schiller-Universität Jena, Germany. He is the current President-Elect of the American Society of Reproductive Immunology, which honored him with the John Herr Award 2009. He is member of the Councils of the European Society of Reproductive Immunology and the International Society for Immunology of Reproduction. Prof. Markert is Associate Editor (since 2010) of the American Journal of Reproductive Immunology and of three |
| books. The scientific focus of Prof. Markert’s group is intracellular signal transduction and microRNA in cells at the materno-fetal interface, mainly trophoblast and NK cells, as well as proteomic analyses of fertility and pregnancy related body fluids. His lab was member of EMBIC, an European Network of Excellence on Embryo Implantation Control (www.embic.org) and is involved in numerous further international cooperations. Prof. Markert was Chair of several international congresses. |
Vera Jonakova, PhD ,Assoc. Prof., RNDr., DrSc.
Sperm surface protein AQN1 spermadhesin and ubiquitin proteasome pathway in porcine anti-polyspermy defense |
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Dr.Vera Jonakova is Senior Scientist in Laboratory of Diagnostics for Reproductive Medicine, Institute of Biotechnology, AS CR,v.v.i., Prague, Czech Republic. Education:1963-1968 – Faculty of Science, Charles University, Prague; 1969 – RNDr. (Rerum Naturalium Doctor);1975 was graduated PhD - Thesis “Structure of trypsin inhibitor from cow colostrum“; 1997 – Associate Professor, Thesis: „Biochemical proces of sperm-egg binding“. 2001 – DrSc., biological sciences – biochemistry, Thesis: “Sperm surface proteins in fertilization.” Postdoctoral research |
| training:1983 – 1992 21 moths in the Institute for Clinical Chemistry and Clinical Biochemistry and Dept. of Andrology, University of Munich, Germany (AvH Foundation Fellowship); 1991 – 2008 – teaching: “Biochemistry of Reproduction”, Faculty of Science, Charles Univ., Prague; supervision of diploma and PhD students; 1992 – 2006 – Head of the Dept. of Biochemistry of Reproduction, IMG, AS CR, Prague. Current research program: proteins from sperm and reproductive fluids. Dr. Jonakova have 91 original publications. e-mail address: vjon@img.cas.cz . |
Viktor Chernyshov, Prof. MD, PhD
Immune system and IVF |
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Dr. Viktor Chernyshov graduated from the Lviv State Medical University with a degree in medicine and a MD in internal medicine. He received PhD at 1970 and Doctor of Medical Sciences at 1980. From 1981 is a Head, Laboratory of Immunology, Institute of Pediatrics, O/G, National Academy of Medical Sciences of Ukraine. From 1988 is Professor of Immunology. Dr.Chernyshov organized four International symposia for Immunology of Reproduction in Kiev (1987- 1996). He was a supervisor of 33 PhD and 4 DSc. He has more than 450 publications in journals |
| and textbooks (“Immunoandrology”, “Immune factors in infertility”, “Ionizing radiation and immune system of children”, “Immune status of system mother-fetus-newborn” in: “Chernobyl Catastrophe”, rus.).72 original articles are quoted in PubMed. Dr.Chernyshov was member of editorial board of Central European Journal of Immunology. He was elected as regional representative (1986-1989), secretary (1989-1995), councilor (1995-1998) of ISIR, councilor (1996-2005) of ESRADI for ( 1982-1985), member councilor (1985-) of ICCI. |
Yehuda Shoenfeld, Professor
The mosaic of autoimmunity; gender ,hormones pregnancy and
autoimmunity
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Dr. Yehuda Shoenfeld was the head of a Department of Medicine since 1984 (age 36), until March 2011, and he has founded in 1985 and is now heading the Center for Autoimmune Diseases, at the largest hospital in Israel- the Sheba Medical Center, which is affiliated to the Sackler Faculty of Medicine in Tel-Aviv University, in Israel. Dr. Shoenfeld is the Incumbent of the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases in Tel-Aviv University. His clinical and scientific works focus on autoimmune /rheumatic diseases, and he |
| has published more than 1600 papers in world known journals. His articles had over 20,000 citations until 2009. He has written more than 350 chapters in books, edited 25 books, some of which became cornerstones in science and clinical practice, such as "The Mosaic of Autoimmunity", "Infections and Autoimmunity" and the textbook "Autoantibodies" and "Diagnostic criteria of autoimmune diseases". He is on the editorial board of 43 journals in the field of rheumatology and autoimmunity, founder and editor of the Israel Medical Association Journal in english, founder and Editor of the "Autoimmunity Reviews" ( IF 6.4) and Co-Editor of "Journal of Autoimmunity" (IF=9.2). For the last 20 years Prof. Shoenfeld is the Editor of "Harefuah" – The Israel journal in medicine (Hebrew) and edited the Israel Medical Encyclopedia (10 volumes, 5000 items). He had organized over 20 international congresses in autoimmunity. Dr. Shoenfeld received in Vienna, the EULAR prize 2005: "The infectious etiology of anti-phospholipid syndrome"; Gold medal from the Slovak Society of Physicians for his contribution to Israel – Slovakia collaboration, and is honorary member of the Hungarian Association of Rheumatology. In UC Davis, USA, Dr. Shoenfeld received the Nelson's Prize for Humanity and Science for 2008. In 2009 he was honored as Doctoris Honoris Causa, from Debrecen University (Hungary) and honorary member of the Slovenian National Academy of Sciences. Dr. Shoenfeld has educated a long list of students. |
Yulia Antsiferova Yulia, MD, PhD
Immunological factors of IVF success |
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Biological Doctor, senior scientific worker of the laboratory of Clinical Immunology of State Research Institute of Maternity and Childhood (Ivanovo, Russia), author more than 200 scientific poublications, scientific superviser of 4 PHD students. |
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Zdenka Ulcova Gallova, Prof., MD, PhD, Dr.Sc.
Does asymptomatic celiac disease influence infertility in women ? |
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Prof. Zdenka Ulcova-Gallova works in the Department of Gynecology and Obstetrics of Medical School of Charles University and Faculty Hospital in Pilsen. A major aim of her activities is to work in the field of gynecology, obstetrics, and reproductive immunology. She has been a chief of a lot of Czech research programmes and co-worker of some international studies. She organised European Congress of Reproductive Immunology in Pilsen, Czech Republic (2004). She is member of nine societies, and of editorial board of two Czech journals. |
| She wrote more than 400 articles concerning of reproductive immunology. You can find her vestiges in six books and one film. www.fnplzen.cz/ulcovagallova |
Will have a lecture also:
1. Jurgen Klinshtain
2. Nasir Rana
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